SCHEMBL7909688

SCHEMBL7909688

CCC[C@H]1CC[C@H](CCCBr)CC1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
LMNA P02545 2/20 0.38
MAPK1 P28482 2/20 0.38
HTT P42858 2/20 0.38
MAPT P10636 2/20 0.34
CYP2C9 P11712 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
ALDH1A1 P00352 1/20 0.32
PKM P14618 1/20 0.32
SIGMAR1 Q99720 2/20 0.30
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7728721 0.93 CYP1A2 (0.41) CYP1A2LMNAMAPK1HTTMAPT
SCHEMBL7728716 0.93 CYP1A2 (0.41) CYP1A2LMNAMAPK1HTTMAPT
SCHEMBL7728724 0.93 CYP1A2 (0.41) CYP1A2LMNAMAPK1HTTMAPT
SCHEMBL31704086 0.93 CYP1A2 (0.44) CYP1A2LMNAMAPK1HTTMAPT
SCHEMBL9553263 0.91 CYP1A2 (0.43) CYP1A2LMNAMAPK1HTTMAPT
SCHEMBL9155708 0.88 CYP1A2 (0.50) CYP1A2LMNAMAPK1HTTMAPT
SCHEMBL9155704 0.88 CYP1A2 (0.50) CYP1A2LMNAMAPK1HTTMAPT
SCHEMBL281878 0.87
SCHEMBL9471037 0.84 CYP1A2 (0.39) CYP1A2LMNAMAPK1HTTMAPT
SCHEMBL8466827 0.84 CYP1A2 (0.39) CYP1A2LMNAMAPK1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750028-B1 Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2001-04-18 EP disclosed
US-5776367-A Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1998-07-07 US disclosed
EP-0750028-A2 Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-12-27 EP disclosed