SCHEMBL7910081

SCHEMBL7910081

CSCCC(NC(=O)c1ccc(COCCc2ccc3ccccc3c2)cc1-c1ccccc1C)C(=O)O.[LiH]

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 13/20 0.64
FNTB P49356 13/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7910088 1.00 FNTA (0.64) FNTAFNTB
SCHEMBL7910344 0.99 FNTA (0.65) FNTAFNTB
SCHEMBL7910343 0.99 FNTA (0.65) FNTAFNTB
SCHEMBL7905820 0.94 FNTA (0.69) FNTAFNTB
SCHEMBL7905822 0.94 FNTA (0.69) FNTAFNTB
SCHEMBL7907153 0.93 FNTA (0.70) FNTAFNTB
SCHEMBL7907155 0.93 FNTA (0.70) FNTAFNTB
SCHEMBL7907233 0.93 FNTA (0.68) FNTAFNTB
SCHEMBL7907238 0.93 FNTA (0.68) FNTAFNTB
SCHEMBL7910550 0.92 FNTA (0.69) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed