Lithium Ion

Lithium Ion

SCHEMBL7910120

CSCC[C@H](NC(=O)c1ccc(COC(CC2CCCCC2)CC2CCCCC2)cc1-c1ccccc1C)C(=O)[O-].[Li+]

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.60
FNTB P49356 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium Ion SCHEMBL7905865 0.97
Lithium Ion SCHEMBL7905067 0.94 FNTA (0.57) FNTAFNTB
Lithium Ion SCHEMBL7904835 0.93
Lithium Ion SCHEMBL7903781 0.93
Lithium Ion SCHEMBL7897803 0.92 FNTA (0.54) FNTAFNTB
SCHEMBL7907268 0.92 FNTA (0.65) FNTAFNTB
SCHEMBL7907265 0.92 FNTA (0.65) FNTAFNTB
Lithium Ion SCHEMBL7906918 0.92 FNTA (0.56) FNTAFNTB
SCHEMBL7910117 0.92 FNTA (0.64) FNTAFNTB
SCHEMBL7910126 0.92 FNTA (0.64) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed