Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910123 | 1.00 | SPHK1 (0.42) | SPHK1SPHK2CYP2C9ESR2ESR1 | |
| SCHEMBL7912841 | 0.91 | SPHK1 (0.42) | SPHK1SPHK2CYP2C9ESR2ESR1 | |
| SCHEMBL7912846 | 0.91 | SPHK1 (0.42) | SPHK1SPHK2CYP2C9ESR2ESR1 | |
| SCHEMBL7912870 | 0.87 | SPHK1 (0.49) | SPHK1SPHK2 | |
| SCHEMBL7912867 | 0.87 | SPHK1 (0.49) | SPHK1SPHK2 | |
| SCHEMBL11276980 | 0.86 | SPHK1 (0.49) | SPHK1SPHK2CYP2C9ESR2ESR1 | |
| SCHEMBL10903218 | 0.85 | CYP2C9 (0.51) | SPHK1SPHK2CYP2C9ESR2ALDH1A1 | |
| SCHEMBL10903223 | 0.85 | CYP2C9 (0.51) | SPHK1SPHK2CYP2C9ESR2ALDH1A1 | |
| SCHEMBL7916221 | 0.84 | SPHK1 (0.52) | SPHK1SPHK2 | |
| SCHEMBL7912857 | 0.84 | SPHK1 (0.52) | SPHK1SPHK2CYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174456-B1 | STABILITY, LOW VISCOSITY AND HIGH TRANSITION TEMPERATURE OF THE ISOTROPIC PHASE | CHISSO CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0857708-A1 | LIQUID CRYSTAL COMPOUNDS HAVING SUBSTITUTED ALKYL GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1998-08-12 | — | — | EP | disclosed |