SCHEMBL7910232

SCHEMBL7910232

CSCC[C@H](NC(=O)c1ccc(OCCCOc2ccccc2)cc1-c1ccccc1C)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 12/20 0.65
FNTB P49356 12/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7903741 0.97 FNTA (0.66) FNTAFNTB
SCHEMBL7905797 0.92 FNTA (0.64) FNTAFNTB
SCHEMBL7905794 0.92 FNTA (0.64) FNTAFNTB
SCHEMBL7905858 0.90 FNTA (0.61) FNTAFNTB
SCHEMBL7904103 0.87 FNTA (0.66) FNTAFNTB
SCHEMBL7904101 0.87 FNTA (0.66) FNTAFNTB
SCHEMBL7897627 0.86 FNTA (0.65) FNTAFNTB
SCHEMBL7905824 0.86 FNTA (0.65) FNTAFNTB
SCHEMBL7905826 0.86 FNTA (0.65) FNTAFNTB
SCHEMBL8643563 0.86 FNTA (0.54) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998050031-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 WO claimed
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed