Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1297076 | 1.00 | EPHX2 (0.49) | EPHX2ALDH1A1PPM1BPTPN1PPP1CC | |
| Ethylene Glycol SCHEMBL1296766 | 0.95 | EPHX2 (0.46) | EPHX2ALDH1A1PPM1BPTPN1PPP1CC | |
| SCHEMBL1297860 | 0.95 | EPHX2 (0.54) | EPHX2PPM1BPTPN1PPP1CCS1PR5 | |
| SCHEMBL28467955 | 0.94 | EPHX2 (0.53) | EPHX2S1PR5HCAR2PPARGTSHR | |
| SCHEMBL19356852 | 0.94 | EPHX2 (0.53) | EPHX2S1PR5HCAR2PPARGTSHR | |
| SCHEMBL1297287 | 0.94 | EPHX2 (0.53) | EPHX2S1PR5HCAR2PPARGTSHR | |
| SCHEMBL1297778 | 0.94 | EPHX2 (0.53) | EPHX2S1PR5HCAR2PPARGTSHR | |
| SCHEMBL1296618 | 0.94 | EPHX2 (0.53) | EPHX2S1PR5HCAR2PPARGTSHR | |
| SCHEMBL5366260 | 0.94 | EPHX2 (0.53) | EPHX2S1PR5HCAR2PPARGTSHR | |
| SCHEMBL1296624 | 0.94 | EPHX2 (0.53) | EPHX2S1PR5HCAR2PPARGTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210956-B1 | USED AS CHIRAL PRECURSORS FOR NON-NATURALLY OCCURING AMINO ACIDS AND POLYESTER; CONTACTING A 1,3-CYCLOHEXANEDICARBOXYLIC ACID DIESTER DERIVATIVE WITH A LIPASE CAPABLE OF CONVERTING IT UNDER AQUEOUS CONDITIONS | EASTMAN CHEMICAL COMPANY | 2001-04-03 | — | — | US | disclosed |
| US-6028213-A | BY CONTACTING WITH A LIPASE UNDER AQUEOUS CONDITIONS TO ENANTIOSELECTIVELY PRODUCE THE ACTIVATOR | EASTMAN CHEMICAL COMPANY (US) | 2000-02-22 | — | — | US | disclosed |