Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582784 | 0.88 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL7900613 | 0.86 | EDNRA (0.57) | EDNRAEDNRB | |
| SCHEMBL7910670 | 0.82 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL6582199 | 0.80 | EDNRA (0.89) | EDNRAEDNRB | |
| SCHEMBL7685248 | 0.78 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL6581605 | 0.78 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL6583479 | 0.78 | EDNRA (0.68) | EDNRAEDNRB | |
| SCHEMBL6584300 | 0.78 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL803855 | 0.75 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6587903 | 0.75 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211223-B1 | BENZODIOXOL-5-YL-2-METHOXY-4-METHYLPHENYLSULFONYLAMINO-2-OXO ETHYL-1-METHYL-1HINDOLE-6-CARBOXYLIC ACID | PFIZER INC. | 2001-04-03 | — | — | US | disclosed |
| WO-1999020623-A1 | INDOLE DERIVATIVE USEFUL AS ENDOTHELIN RECEPTOR ANTAGONIST | PFIZER LIMITED (GB) | 1999-04-29 | — | — | WO | disclosed |