Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550777 | 0.89 | MAOB (0.47) | MAOBNR4A2SMPD1GPR132SRD5A2 | |
| SCHEMBL8547589 | 0.88 | MAOB (0.47) | MAOBNR4A2SMPD1GPR132SRD5A2 | |
| SCHEMBL7900921 | 0.86 | MAOB (0.54) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL7901041 | 0.86 | MAOB (0.54) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL7900916 | 0.86 | MAOB (0.54) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL8550778 | 0.85 | MAOB (0.48) | MAOBNR4A2SMPD1GPR132SRD5A2 | |
| SCHEMBL7908740 | 0.84 | MAOB (0.51) | MAOBNR4A2SMPD1GPR132SRD5A2 | |
| SCHEMBL7908745 | 0.84 | MAOB (0.51) | MAOBNR4A2SMPD1GPR132SRD5A2 | |
| SCHEMBL8545812 | 0.84 | MAOB (0.51) | MAOBNR4A2SMPD1GPR132SRD5A2 | |
| Water SCHEMBL7914345 | 0.83 | MAOB (0.50) | MAOBNR4A2SMPD1GPR132SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | claimed |
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |