SCHEMBL7910936

SCHEMBL7910936

O=C(O)CCC(Oc1cc(OCc2ccccc2)ccc1C(=O)O)c1ccccc1

nearest known ligand 0.84

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.46
MAOB P27338 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7910938 1.00 FFAR1 (0.46) FFAR1MAOBFFAR4
SCHEMBL7907678 0.91 MAOB (0.56) MAOB
SCHEMBL7907710 0.91 PARP15 (0.47) FFAR1
SCHEMBL7907683 0.91 MAOB (0.56) MAOB
SCHEMBL7907705 0.91 PARP15 (0.47) FFAR1
SCHEMBL7914053 0.89 FFAR4 (0.48) MAOBFFAR4
SCHEMBL7914050 0.89 FFAR4 (0.48) MAOBFFAR4
SCHEMBL7907640 0.88 MAOB (0.45) MAOB
SCHEMBL7907642 0.88 MAOB (0.45) MAOB
SCHEMBL7907396 0.87 NMT1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728128-B1 SUBSTITUTED PHENYL COMPOUNDS RHONE POULENC RORER LTD (GB) 1998-09-16 EP claimed
EP-0728128-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1996-08-28 EP claimed
WO-1995013262-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1995-05-18 WO claimed
US-6211234-B1 BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID RHONE-POULENC RORER LIMITED (GB) 2001-04-03 US disclosed
EP-0728128-B1 SUBSTITUTED PHENYL COMPOUNDS RHONE POULENC RORER LTD (GB) 1998-09-16 EP disclosed
EP-0728128-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1996-08-28 EP disclosed
WO-1995013262-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1995-05-18 WO disclosed