Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25081993 | 0.89 | PLA2G4B (0.71) | PLA2G4BPTPN11CYP4F2CYP4A11LTB4R | |
| SCHEMBL30278806 | 0.89 | PLA2G4B (0.71) | PLA2G4BPTPN11CYP4F2CYP4A11LTB4R | |
| SCHEMBL25081988 | 0.89 | PLA2G4B (0.71) | PLA2G4BPTPN11CYP4F2CYP4A11LTB4R | |
| SCHEMBL25081987 | 0.89 | PLA2G4B (0.71) | PLA2G4BPTPN11CYP4F2CYP4A11LTB4R | |
| SCHEMBL30278812 | 0.89 | PLA2G4B (0.71) | PLA2G4BPTPN11CYP4F2CYP4A11LTB4R | |
| SCHEMBL25081990 | 0.88 | PLA2G4B (0.68) | PLA2G4BFFAR1PTPN11CYP4F2CYP4A11 | |
| SCHEMBL30278815 | 0.88 | PLA2G4B (0.68) | PLA2G4BFFAR1PTPN11CYP4F2CYP4A11 | |
| SCHEMBL415441 | 0.86 | FFAR1 (0.68) | FFAR1FFAR4SRD5A2NR3C1 | |
| SCHEMBL3508233 | 0.85 | PLA2G4B (0.56) | PLA2G4BFFAR1FFAR4CYP4F2CYP4A11 | |
| SCHEMBL30278807 | 0.84 | PLA2G4B (0.64) | PLA2G4BFFAR1PTPN11CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999064041-A9 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | ADVANCED MEDICINE INC (US) | 2001-05-31 | — | — | WO | disclosed |
| EP-1100519-A1 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | Advanced Medicine, Inc. (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-1999064041-A1 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |