SCHEMBL7911535

SCHEMBL7911535

C=C/C=C\C=C/C/C=C/C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.41
TSHR P16473 3/20 0.41
GABRR1 P24046 2/20 0.41
GABRR2 P28476 2/20 0.41
BLM P54132 2/20 0.41
LMNA P02545 2/20 0.41
GABRR3 A8MPY1 1/20 0.41
APEX1 P27695 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
EGLN3 Q9H6Z9 1/20 0.35
OXER1 Q8TDS5 2/20 0.33
ALOX12 P18054 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3504409 0.78 PPARA (0.59) PPARATSHRGABRR1GABRR2BLM
SCHEMBL96612 0.78
SCHEMBL1649611 0.78 TSHR (0.44) PPARATSHRGABRR1GABRR2BLM
SCHEMBL28915767 0.78 TSHR (0.44) PPARATSHRGABRR1GABRR2BLM
SCHEMBL4436498 0.78
SCHEMBL29958938 0.78 TSHR (0.44) PPARATSHRGABRR1GABRR2BLM
SCHEMBL1649613 0.78 TSHR (0.44) PPARATSHRGABRR1GABRR2BLM
SCHEMBL13448114 0.78
SCHEMBL3504406 0.78 PPARA (0.59) PPARATSHRGABRR1GABRR2BLM
SCHEMBL2487545 0.78 TSHR (0.44) PPARATSHRGABRR1GABRR2BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010095849-A2 ACID ADDITION SALT OF UDENAFIL, PREPARATION METHOD THEREOF AND PHAMACEUTICAL COMPOSITION COMPRISING THE SAME DONG-A PHARM. CO., LTD. (KR) 2010-08-26 WO disclosed