Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572442 | 0.89 | MEN1 (0.76) | MEN1KMT2AALDH1A1CES2CES1 | |
| SCHEMBL31103641 | 0.89 | MEN1 (0.76) | MEN1KMT2AALDH1A1CES2CES1 | |
| Methyl Benzoate SCHEMBL29102092 | 0.88 | MEN1 (0.71) | MEN1KMT2AALDH1A1CES2CES1 | |
| Ammonia Solution, Strong SCHEMBL27704150 | 0.88 | MEN1 (0.74) | MEN1KMT2AALDH1A1CES2CES1 | |
| SCHEMBL27858189 | 0.88 | MEN1 (0.74) | MEN1KMT2AALDH1A1CES2CES1 | |
| Fluoride SCHEMBL28307367 | 0.88 | MEN1 (0.74) | MEN1KMT2AALDH1A1CES2CES1 | |
| Methane SCHEMBL28043489 | 0.88 | MEN1 (0.74) | MEN1KMT2AALDH1A1CES2CES1 | |
| Dinitrophenylene SCHEMBL27567750 | 0.86 | MEN1 (0.64) | MEN1KMT2AALDH1A1CES2CES1 | |
| SCHEMBL31067505 | 0.85 | MAPT (0.67) | MEN1KMT2AALDH1A1CES2CES1 | |
| SCHEMBL4470153 | 0.85 | MAPT (0.67) | MEN1KMT2AALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |