Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | AHCY | P23526 | 1/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28420023 | 0.85 | SCN2A (0.37) | DYRK1ASCN2ASCN9ASCN3ASCN10A | |
| SCHEMBL7361765 | 0.81 | DYRK1A (0.41) | DYRK1ASCN2APLAUGAAHTT | |
| SCHEMBL4596087 | 0.81 | DYRK1A (0.41) | DYRK1ASCN2APLAUGAAHTT | |
| SCHEMBL29509758 | 0.77 | DYRK1A (0.38) | DYRK1ASCN2A | |
| SCHEMBL22831886 | 0.77 | DYRK1A (0.38) | DYRK1ASCN2A | |
| SCHEMBL15662633 | 0.77 | DYRK1A (0.38) | DYRK1ASCN2A | |
| SCHEMBL11708509 | 0.77 | HPGD (0.40) | DYRK1ASCN2ASCN9ASCN3ASCN10A | |
| SCHEMBL2223631 | 0.77 | PLAU (0.50) | DYRK1ASCN2ASCN9ASCN3ASCN10A | |
| SCHEMBL15661581 | 0.74 | HTT (0.44) | DYRK1ASCN2APLAUGAAHTT | |
| SCHEMBL19616230 | 0.74 | FYN (0.40) | DYRK1AGAAUSP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |
| US-6214801-B1 | INHIBITION OF DNA OR RNA VIRAL PROLIFERATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2001-04-10 | — | — | US | disclosed |
| WO-1997027205-A1 | IMIDAZO[1,2-A]PYRIDINE C-NUCLEOSIDES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-07-31 | — | — | WO | disclosed |
| US-5216171-A | Nitrification inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0453883-A2 | 2-amino-4-trichloropyridine derivatives | BASF Aktiengesellschaft (DE) | 1991-10-30 | — | — | EP | disclosed |