SCHEMBL7912459

SCHEMBL7912459

O=C1CC(=O)c2c(ccc3ccccc23)C1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.55
ALDH1A1 P00352 4/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
MAPT P10636 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
RAB9A P51151 1/20 0.51
CES1 P23141 4/20 0.43
BCHE P06276 1/20 0.42
CYP1A2 P05177 2/20 0.42
HPGD P15428 2/20 0.42
CYP2C19 P33261 2/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX12 P18054 1/20 0.42
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29963125 0.89 DNMT1 (0.53) DNMT1ALDH1A1MEN1KMT2AMAPT
SCHEMBL1501682 0.89 DNMT1 (0.53) DNMT1ALDH1A1MEN1KMT2AMAPT
SCHEMBL938983 0.85 DNMT1 (0.59) DNMT1ALDH1A1MEN1KMT2AMAPT
SCHEMBL12236188 0.80 DNMT1 (0.67) DNMT1ALDH1A1MEN1KMT2AMAPT
SCHEMBL30362207 0.80 DNMT1 (0.67) DNMT1ALDH1A1MEN1KMT2AMAPT
SCHEMBL19230420 0.80 DNMT1 (0.73) DNMT1ALDH1A1MEN1KMT2AMAPT
SCHEMBL7122517 0.80 DNMT1 (0.73) DNMT1ALDH1A1MEN1KMT2AMAPT
SCHEMBL12070492 0.79 DNMT1 (0.51) DNMT1ALDH1A1MEN1KMT2AMAPT
SCHEMBL19230424 0.79 DNMT1 (0.78) DNMT1ALDH1A1MEN1KMT2AMAPT
SCHEMBL29466071 0.79 DNMT1 (0.71) DNMT1ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed