Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832384 | 0.87 | TSHR (0.58) | TSHRUSP2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL10416259 | 0.83 | TSHR (0.56) | TSHRUSP2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL7910513 | 0.82 | TSHR (0.64) | TSHRUSP2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL9832010 | 0.81 | TSHR (0.54) | TSHRUSP2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL8359076 | 0.81 | TSHR (0.54) | TSHRUSP2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL9002375 | 0.79 | TSHR (0.60) | TSHRUSP2ALDH1A1POLBLMNA | |
| SCHEMBL9831798 | 0.79 | TSHR (0.54) | TSHRUSP2ALDH1A1POLBLMNA | |
| SCHEMBL9831662 | 0.77 | TSHR (0.58) | TSHRUSP2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL9831646 | 0.77 | TSHR (0.58) | TSHRUSP2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL9833000 | 0.77 | TSHR (0.58) | TSHRUSP2ALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211438-B1 | FOR CROPS WHICH ARE RESISTANT TO HERBICIDES, AND WHICH GENETICALLY TRANSMIT THIS CHARACTERISTIC TO THEIR PROGENY | MGI PHARMA, INC. | 2001-04-03 | — | — | US | claimed |
| US-6211439-B1 | FOR CROPS WHICH ARE RESISTANT TO HERBICIDES, AND WHICH GENETICALLY TRANSMIT THIS CHARACTERISTIC TO THEIR PROGENY | MGI PHARMA, INC | 2001-04-03 | — | — | US | claimed |