Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912583 | 0.94 | SPHK1 (0.36) | SPHK1SPHK2ESR2 | |
| SCHEMBL7912579 | 0.94 | SPHK1 (0.36) | SPHK1SPHK2ESR2 | |
| SCHEMBL9458448 | 0.86 | SPHK1 (0.42) | SPHK1SPHK2ESR2 | |
| SCHEMBL9458444 | 0.86 | SPHK1 (0.42) | SPHK1SPHK2ESR2 | |
| SCHEMBL7909912 | 0.85 | SPHK1 (0.34) | SPHK1SPHK2ESR2 | |
| SCHEMBL7909919 | 0.85 | SPHK1 (0.34) | SPHK1SPHK2ESR2 | |
| SCHEMBL9480875 | 0.84 | SPHK1 (0.43) | SPHK1SPHK2ESR2 | |
| SCHEMBL9480882 | 0.84 | SPHK1 (0.43) | SPHK1SPHK2ESR2 | |
| SCHEMBL7910905 | 0.83 | SPHK1 (0.53) | SPHK1SPHK2 | |
| SCHEMBL7902403 | 0.82 | SPHK1 (0.56) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174456-B1 | STABILITY, LOW VISCOSITY AND HIGH TRANSITION TEMPERATURE OF THE ISOTROPIC PHASE | CHISSO CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |