Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912777 | 0.91 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL7910049 | 0.90 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL7910053 | 0.90 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL7910044 | 0.90 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL7902597 | 0.87 | CYP2C9 (0.59) | CYP2C9ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL7902594 | 0.87 | CYP2C9 (0.59) | CYP2C9ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL4804721 | 0.87 | CYP2C9 (0.55) | CYP2C9ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL4804733 | 0.87 | CYP2C9 (0.55) | CYP2C9ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL7910947 | 0.86 | SPHK1 (0.41) | CYP2C9ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL7910943 | 0.86 | SPHK1 (0.41) | CYP2C9ALDH1A1LMNAMAPTESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174456-B1 | STABILITY, LOW VISCOSITY AND HIGH TRANSITION TEMPERATURE OF THE ISOTROPIC PHASE | CHISSO CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |