SCHEMBL7912849

SCHEMBL7912849

OC[C@@H]1[C@@H](O)[C@@H](O)CN1Cc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 8/20 0.72
GAA P10253 5/20 0.72
MGAM O43451 4/20 0.61
FUCA1 P04066 2/20 0.57
UGCG Q16739 2/20 0.54
GBA2 Q9HCG7 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2265347 1.00 GBA1 (0.72) GBA1GAAMGAMFUCA1UGCG
SCHEMBL6135325 1.00 GBA1 (0.72) GBA1GAAMGAMFUCA1UGCG
SCHEMBL2433104 1.00 GBA1 (0.72) GBA1GAAMGAMFUCA1UGCG
SCHEMBL2268885 1.00 GBA1 (0.72) GBA1GAAMGAMFUCA1UGCG
SCHEMBL7911357 1.00 GBA1 (0.72) GBA1GAAMGAMFUCA1UGCG
SCHEMBL7908086 0.95 MGAM (0.68) GBA1GAAMGAMFUCA1UGCG
SCHEMBL2266205 0.95 MGAM (0.68) GBA1GAAMGAMFUCA1UGCG
SCHEMBL7911388 0.95 MGAM (0.68) GBA1GAAMGAMFUCA1UGCG
SCHEMBL7911362 0.95 MGAM (0.68) GBA1GAAMGAMFUCA1UGCG
SCHEMBL2435939 0.95 MGAM (0.68) GBA1GAAMGAMFUCA1UGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0624652-B1 Process for producing N-substituted polyhydroxy nitrogen-containing heterocycles MONSANTO CO (US) 2001-10-10 EP disclosed
US-5695969-A Process for producing N-substituted polyhydroxy nitrogen-containing heterocycles MONSANTO COMPANY (US) 1997-12-09 US disclosed
US-5401645-A Process for producing n-substituted polyhydroxy nitrogen-containing heterocycles utilizing acetobacteraceae and corynebacterium MONSANTO COMPANY (US) 1995-03-28 US disclosed
EP-0624652-A1 Process for producing N-substituted polyhydroxy nitrogen-containing heterocycles MONSANTO COMPANY (US) 1994-11-17 EP disclosed
EP-0322395-B1 HETEROCYCLIC COMPOUNDS FOR INHIBITING VIRUS Monsanto Company (US) 1993-03-24 EP disclosed
US-5089520-A Administering 1,4-dideoxy-1,4-imino-L-arabinitol or 1,4-dideoxy-1,4-imino-D-ribitol; human immunodeficiency virus MONSANTO COMPANY (US) 1992-02-18 US disclosed
US-5043416-A Method of inhibiting virus MONSANTO COMPANY (US) 1991-08-27 US disclosed
US-4999360-A Treatment of AIDS, polyhydroxy piperidine derivatives MONSANTO COMPANY (US) 1991-03-12 US disclosed
EP-0322395-A1 Heterocyclic compounds for inhibiting virus Monsanto Company (US) 1989-06-28 EP disclosed