Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | HTT | P42858 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27965124 | 0.89 | KMT2A (0.79) | KMT2ANPSR1MEN1HTTALDH1A1 | |
| SCHEMBL7904930 | 0.84 | NPSR1 (1.00) | KMT2ANPSR1MEN1HTTALDH1A1 | |
| SCHEMBL7915167 | 0.84 | HTT (0.73) | KMT2ANPSR1MEN1HTTALDH1A1 | |
| SCHEMBL7914973 | 0.84 | NPSR1 (0.73) | KMT2ANPSR1MEN1HTTALDH1A1 | |
| SCHEMBL7914925 | 0.84 | NPSR1 (0.78) | KMT2ANPSR1MEN1HTTALDH1A1 | |
| SCHEMBL7904890 | 0.84 | NPSR1 (0.61) | KMT2ANPSR1MEN1HTTALDH1A1 | |
| SCHEMBL7918574 | 0.81 | NPSR1 (0.72) | KMT2ANPSR1MEN1HTTALDH1A1 | |
| SCHEMBL7918635 | 0.81 | HTT (0.72) | KMT2ANPSR1MEN1HTTALDH1A1 | |
| SCHEMBL7912126 | 0.81 | KMT2A (0.68) | KMT2ANPSR1MEN1HTTALDH1A1 | |
| SCHEMBL7918468 | 0.81 | NPSR1 (0.69) | KMT2ANPSR1MEN1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |