SCHEMBL7913864

SCHEMBL7913864

CCCCC[C@H]1CC[C@H](CCc2ccc([C@H]3CC[C@H](CCCCC)CC3)cc2)CC1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 13/20 0.59
SPHK2 Q9NRA0 7/20 0.51
CYP2C9 P11712 1/20 0.47
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913866 1.00 SPHK1 (0.59) SPHK1SPHK2CYP2C9MEN1KMT2A
SCHEMBL8035415 0.98 SPHK1 (0.57) SPHK1SPHK2CYP2C9MEN1KMT2A
SCHEMBL10902542 0.98 SPHK1 (0.57) SPHK1SPHK2CYP2C9MEN1KMT2A
SCHEMBL10901561 0.98 SPHK1 (0.57) SPHK1SPHK2CYP2C9MEN1KMT2A
SCHEMBL10902554 0.98 SPHK1 (0.57) SPHK1SPHK2CYP2C9MEN1KMT2A
SCHEMBL8035421 0.98 SPHK1 (0.57) SPHK1SPHK2CYP2C9MEN1KMT2A
SCHEMBL10479901 0.98 SPHK1 (0.57) SPHK1SPHK2CYP2C9MEN1KMT2A
SCHEMBL10479897 0.98 SPHK1 (0.57) SPHK1SPHK2CYP2C9MEN1KMT2A
SCHEMBL10479671 0.97 SPHK1 (0.56) SPHK1SPHK2CYP2C9MEN1KMT2A
SCHEMBL10624625 0.97 SPHK1 (0.56) SPHK1SPHK2CYP2C9MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US disclosed
US-5387369-A With specified mixture of components; short switching times MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-07 US disclosed
EP-0394417-B1 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1994-10-26 EP disclosed
EP-0394417-A1 SUPERTWIST LIQUID CRYSTAL DISPLAY. MERCK PATENT GMBH (DE) 1990-10-31 EP disclosed
WO-1990004622-A1 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-05-03 WO disclosed
US-4583826-A Phenylethanes HOFFMANN-LA ROCHE INC. (US) 1986-04-22 US disclosed