SCHEMBL7913992

SCHEMBL7913992

CCCCCC1CCC(C2CCC(c3ccc(OC(F)(F)C(F)C(F)(F)F)c(F)c3)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
RECQL P46063 1/20 0.32
MGLL Q99685 2/20 0.32
KDM1A O60341 2/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8834519 1.00 GAA (0.32) GAAMAPTRECQLMGLLKDM1A
SCHEMBL8834410 0.99 GAA (0.33) GAAMAPTRECQLMGLLKDM1A
SCHEMBL7917430 0.97 MAPT (0.33) GAAMAPTRECQLMGLLKDM1A
SCHEMBL7914004 0.93 CYP2C9 (0.37) MAPTRECQLMGLLKDM1ACYP2C9
SCHEMBL8834211 0.93 CYP2C9 (0.37) MAPTRECQLMGLLKDM1ACYP2C9
SCHEMBL7913665 0.90 PPARG (0.34) GAAMAPTRECQLMGLLCYP2C9
SCHEMBL7903494 0.90 PPARG (0.34) GAAMAPTRECQLMGLLCYP2C9
SCHEMBL8834284 0.89 GAA (0.32) GAAMAPTCYP2C9
SCHEMBL7911864 0.89 CYP2C9 (0.39) MAPTRECQLMGLLKDM1ACYP2C9
SCHEMBL7911103 0.89 MAPT (0.33) GAAMAPTRECQLMGLLCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed