Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243779 | 1.00 | MEN1 (0.32) | MEN1KMT2ALMNAELANEPLCG1 | |
| SCHEMBL3247087 | 1.00 | MEN1 (0.32) | MEN1KMT2ALMNAELANEPLCG1 | |
| SCHEMBL3247082 | 1.00 | MEN1 (0.32) | MEN1KMT2ALMNAELANEPLCG1 | |
| SCHEMBL3242715 | 0.90 | KMT2A (0.34) | MEN1KMT2ALMNAELANEPLCG1 | |
| SCHEMBL3242691 | 0.90 | KMT2A (0.34) | MEN1KMT2ALMNAELANEPLCG1 | |
| SCHEMBL7915963 | 0.90 | KMT2A (0.34) | MEN1KMT2ALMNAELANEPLCG1 | |
| SCHEMBL3242716 | 0.90 | KMT2A (0.34) | MEN1KMT2ALMNAELANEPLCG1 | |
| SCHEMBL3243574 | 0.87 | BRAF (0.38) | MEN1KMT2ALMNA | |
| SCHEMBL3243568 | 0.87 | BRAF (0.38) | MEN1KMT2ALMNA | |
| SCHEMBL3243570 | 0.87 | BRAF (0.38) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056195-A1 | NEW COMPOUNDS 575 | ASTRAZENECA AB (SE) | 2010-05-20 | — | — | WO | disclosed |