SCHEMBL7914906

SCHEMBL7914906

CCCCCCCCCCCCCCCCCCCCCCCC(=O)N(C)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
FFAR4 Q5NUL3 1/20 0.40
FFAR1 O14842 1/20 0.40
KDM4E B2RXH2 1/20 0.40
DUSP3 P51452 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515728 1.00 EPHX2 (0.41) EPHX2MEN1KMT2AFFAR4FFAR1
SCHEMBL15977917 1.00 EPHX2 (0.41) EPHX2MEN1KMT2AFFAR4FFAR1
SCHEMBL788641 1.00 EPHX2 (0.41) EPHX2MEN1KMT2AFFAR4FFAR1
SCHEMBL25206528 1.00 EPHX2 (0.41) EPHX2MEN1KMT2AFFAR4FFAR1
SCHEMBL198354 1.00 EPHX2 (0.41) EPHX2MEN1KMT2AFFAR4FFAR1
SCHEMBL23234144 1.00 EPHX2 (0.41) EPHX2MEN1KMT2AFFAR4FFAR1
SCHEMBL18970877 1.00 EPHX2 (0.41) EPHX2MEN1KMT2AFFAR4FFAR1
SCHEMBL23016820 1.00 EPHX2 (0.41) EPHX2MEN1KMT2AFFAR4FFAR1
SCHEMBL61278 1.00 EPHX2 (0.41) EPHX2MEN1KMT2AFFAR4FFAR1
SCHEMBL31314689 1.00 EPHX2 (0.41) EPHX2MEN1KMT2AFFAR4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6210691-B1 LIPOPHILIC DERIVATIVES OF AMINO DEOXYALDITOLS, SHAMPOOS AND HAIR CONDITIONERS L'OREAL (FR) 2001-04-03 US disclosed
US-6001376-A COSMETIC COMPOSITIONS FOR THE TREATMENT OF KERATINOUS SUBSTANCES AND FOR BUCCODENTAL HYGIENE L'OREAL (FR) 1999-12-14 US disclosed
EP-0648204-B1 AMINO DEOXYALDITOL LIPOPHILIC DERIVATIVES FOR USE IN COSMETICS, COSMETIC COMPOSITIONS CONTAINING SAME AND NOVEL ALKYL CARBAMATES OREAL (FR) 1998-11-18 EP disclosed
US-5616746-A SKIN AND HAIR TREATMENT L'OREAL 1997-04-01 US disclosed
EP-0648204-A1 AMINO DEOXYALDITOL LIPOPHILIC DERIVATIVES FOR USE IN COSMETICS, COSMETIC COMPOSITIONS CONTAINING SAME AND NOVEL ALKYL CARBAMATES L'OREAL (FR) 1995-04-19 EP disclosed
WO-1994024097-A1 AMINO DEOXYALDITOL LIPOPHILIC DERIVATIVES FOR USE IN COSMETICS, COSMETIC COMPOSITIONS CONTAINING SAME AND NOVEL ALKYL CARBAMATES L'OREAL (FR) 1994-10-27 WO disclosed