Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589653 | 0.92 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL7915085 | 0.91 | FNTA (0.67) | FNTAFNTB | |
| SCHEMBL7915080 | 0.91 | FNTA (0.67) | FNTAFNTB | |
| SCHEMBL7915074 | 0.91 | FNTA (0.67) | FNTAFNTB | |
| Lithium Ion SCHEMBL7916446 | 0.85 | FNTA (0.60) | FNTAFNTB | |
| Lithium Ion SCHEMBL7905817 | 0.84 | FNTA (0.73) | FNTAFNTB | |
| SCHEMBL7918084 | 0.83 | FNTA (0.73) | FNTAFNTB | |
| SCHEMBL7918098 | 0.83 | FNTA (0.73) | FNTAFNTB | |
| SCHEMBL7918090 | 0.83 | FNTA (0.73) | FNTAFNTB | |
| Lithium Ion SCHEMBL7910084 | 0.82 | FNTA (0.66) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |