Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915462 | 0.92 | HTT (0.85) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7919379 | 0.86 | POLB (0.76) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6907398 | 0.84 | POLB (0.72) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL27923049 | 0.82 | POLB (0.70) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL5478291 | 0.82 | POLB (0.69) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL5582634 | 0.82 | HTT (0.69) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7914187 | 0.81 | HTT (0.68) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11745025 | 0.81 | POLB (0.68) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10805170 | 0.81 | POLB (0.68) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10804640 | 0.80 | POLB (0.74) | POLBHTTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207809-B1 | CATALYTIC HYDROGENATION USING THE CORRESPONDING NITRO COMPOUND | CLARIANT GMBH (DE) | 2001-03-27 | — | — | US | disclosed |