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SCHEMBL7915593

SCHEMBL7915593

CC[C@H]1CC[C@H](CCc2ccc(C(F)(F)Oc3ccc(F)c(F)c3)cc2)CC1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ KCNH2 Q12809 2/20 0.31
▸ FFAR4 Q5NUL3 1/20 0.31
▸ CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915598 1.00 MAOB (0.34) MAOBALDH1A1MAPTHTTL3MBTL1
SCHEMBL8741892 0.93 MAOB (0.34) MAOBALDH1A1MAPTHTTL3MBTL1
SCHEMBL7902063 0.93 MAOB (0.34) MAOBALDH1A1MAPTHTTL3MBTL1
SCHEMBL7909946 0.91 HRH3 (0.34) MAOB
SCHEMBL7909953 0.91 HRH3 (0.34) MAOB
SCHEMBL7912105 0.90 TDP1 (0.34) MAOB
SCHEMBL7912099 0.90 TDP1 (0.34) MAOB
SCHEMBL7735401 0.90 MAOB (0.35) MAOBKCNH2
SCHEMBL7735402 0.90 MAOB (0.35) MAOBKCNH2
SCHEMBL7731617 0.89 MAOB (0.35) MAOBKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786509-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY CHISSO CORP (JP) 2001-09-12 — — EP disclosed
EP-0786509-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1997-07-30 — — EP disclosed