SCHEMBL7916024

SCHEMBL7916024

CC(C)Cc1cc(C2(c3cc(CC(C)C)c(O)c(C(C)C)c3)CC(C)CC(C)(C)C2)cc(C(C)C)c1O

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913477 0.89 ESR1 (0.48) ESR1ESR2
SCHEMBL299794 0.87 ESR1 (0.56) ESR1ESR2GABRA1GABRB1
SCHEMBL7916026 0.87 ESR1 (0.46) ESR1ESR2GABRA1GABRB1
SCHEMBL7916039 0.86 ESR1 (0.48) ESR1ESR2GABRA1
SCHEMBL7068232 0.86 ESR1 (0.48) ESR1ESR2GABRA1
SCHEMBL7063140 0.84 ESR1 (0.46) ESR1ESR2GABRA1
SCHEMBL297898 0.84 ESR1 (0.50) ESR1ESR2GABRA1GABRB1
SCHEMBL7064600 0.82 ESR1 (0.51) ESR1ESR2GABRA1GABRB1
SCHEMBL298231 0.81 ESR1 (0.50) ESR1ESR2GABRA1GABRB1
SCHEMBL7914460 0.80 ESR1 (0.56) ESR1ESR2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284931-B1 REACTION OF 3,3,5-TRIMETHYLCYCLOHEXANONE AND PHENOL TO FORM DIPHENOL DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2001-09-04 US disclosed
EP-0995737-A1 Process for producing 3,3,5-trimethylcyclohexylidenebisphenols Honshu Chemical Industry Co. Ltd. (JP) 2000-04-26 EP disclosed