Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | ARG1 | P05089 | 1/20 | 0.44 |
| ▸ | ARG2 | P78540 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916235 | 1.00 | SLC6A2 (0.52) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| Hydrochloric Acid SCHEMBL7736853 | 0.98 | SLC6A2 (0.50) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| Hydrochloric Acid SCHEMBL7736852 | 0.98 | SLC6A2 (0.50) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL27880111 | 0.90 | SLC6A2 (0.49) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL5329866 | 0.84 | BLM (0.64) | BLMCYP3A4CYP1A2ARG1ARG2 | |
| SCHEMBL10935109 | 0.84 | BLM (0.64) | BLMCYP3A4CYP1A2ARG1ARG2 | |
| SCHEMBL5329860 | 0.84 | BLM (0.64) | BLMCYP3A4CYP1A2ARG1ARG2 | |
| SCHEMBL27880060 | 0.84 | BLM (0.46) | BLMCYP3A4CYP1A2ARG1ARG2 | |
| SCHEMBL2172319 | 0.84 | SMN1; SMN2 (0.60) | SLC6A2BLMCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9457635 | 0.84 | SMN1; SMN2 (0.60) | SLC6A2BLMCYP3A4CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073434-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055330-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-04 | — | — | WO | disclosed |