SCHEMBL7916248

SCHEMBL7916248

CCCCC[C@H]1CC[C@H]([C@H]2CC[C@H](CCc3ccc(-c4ccc(CCCCCF)cc4F)c(F)c3)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.39
HTR2A P28223 3/20 0.38
CYP3A4 P08684 1/20 0.36
CYP2C8 P10632 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
S1PR3 Q99500 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
GPR3 P46089 1/20 0.36
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 1/20 0.34
DRD2 P14416 1/20 0.34
HTR2C P28335 1/20 0.34
SPHK1 Q9NYA1 3/20 0.34
RARA P10276 1/20 0.34
RARG P13631 1/20 0.34
HTR1A P08908 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7916243 1.00 RARB (0.39) RARBHTR2ACYP3A4CYP2C8CYP2D6
SCHEMBL7916242 1.00 RARB (0.39) RARBHTR2ACYP3A4CYP2C8CYP2D6
SCHEMBL7916241 1.00 RARB (0.39) RARBHTR2ACYP3A4CYP2C8CYP2D6
SCHEMBL9187799 0.85 RARB (0.55) RARBHTR2ACYP3A4CYP2C8CYP2D6
SCHEMBL9187787 0.85 RARB (0.55) RARBHTR2ACYP3A4CYP2C8CYP2D6
SCHEMBL7912587 0.84 HSD17B10 (0.43) RARBHTR2ACYP3A4ITGB3ITGA2B
SCHEMBL7912594 0.84 HSD17B10 (0.43) RARBHTR2ACYP3A4ITGB3ITGA2B
SCHEMBL7912592 0.84 HSD17B10 (0.43) RARBHTR2ACYP3A4ITGB3ITGA2B
SCHEMBL4803479 0.83 CYP3A4 (0.39) CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19
SCHEMBL8771230 0.83 CYP3A4 (0.39) CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6174456-B1 STABILITY, LOW VISCOSITY AND HIGH TRANSITION TEMPERATURE OF THE ISOTROPIC PHASE CHISSO CORPORATION (JP) 2001-01-16 US disclosed
EP-0857708-A1 LIQUID CRYSTAL COMPOUNDS HAVING SUBSTITUTED ALKYL GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1998-08-12 EP disclosed