Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 20/20 | 0.66 |
| ▸ | AVPR1A | P37288 | 20/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | OXTR | P30559 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2502226 | 0.91 | AVPR2 (0.59) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL2500582 | 0.88 | AVPR2 (0.68) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL2512459 | 0.88 | AVPR2 (0.72) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL2506775 | 0.84 | AVPR2 (0.64) | AVPR2AVPR1A | |
| SCHEMBL2498442 | 0.83 | AVPR2 (0.63) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL2444038 | 0.82 | AVPR2 (0.60) | AVPR2AVPR1A | |
| SCHEMBL6929168 | 0.82 | AVPR2 (0.74) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL6926726 | 0.82 | AVPR2 (0.74) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL2516823 | 0.80 | AVPR2 (0.61) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL28026991 | 0.80 | AVPR2 (0.61) | AVPR2AVPR1ASLC6A2OXTROPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373632-B1 | SUBSTITUTED BENZYL AND PHENYLSULFONYL TRIAZOLONES, AND USE THEREOF | BAYER IP GMBH (DE) | 2015-03-04 | — | — | EP | disclosed |
| EP-2373632-B1 | SUBSTITUTED BENZYL AND PHENYLSULFONYL TRIAZOLONES, AND USE THEREOF | BAYER IP GMBH (DE) | 2015-03-04 | — | — | EP | disclosed |
| US-8859601-B2 | Substituted benzyl and phenylsulfonyl triazolones, and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-14 | — | — | US | disclosed |
| US-8859601-B2 | Substituted benzyl and phenylsulfonyl triazolones, and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-14 | — | — | US | disclosed |
| WO-2010063402-A1 | SUBSTITUTED BENZYL AND PHENYLSULFONYL TRIAZOLONES, AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-10 | — | — | WO | disclosed |