Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 14/20 | 0.62 |
| ▸ | CA9 | Q16790 | 14/20 | 0.62 |
| ▸ | CA1 | P00915 | 6/20 | 0.62 |
| ▸ | CA6 | P23280 | 3/20 | 0.62 |
| ▸ | CA7 | P43166 | 3/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA4 | P22748 | 2/20 | 0.62 |
| ▸ | CA3 | P07451 | 1/20 | 0.62 |
| ▸ | CA5A | P35218 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907493 | 1.00 | CA12 (0.62) | CA12CA9CA1CA6CA7 | |
| SCHEMBL7906950 | 1.00 | CA12 (0.62) | CA12CA9CA1CA6CA7 | |
| SCHEMBL7917179 | 1.00 | CA12 (0.62) | CA12CA9CA1CA6CA7 | |
| SCHEMBL7921015 | 0.99 | CA12 (0.64) | CA12CA9CA1CA6CA7 | |
| SCHEMBL7921006 | 0.96 | CA12 (0.64) | CA12CA9CA1CA6CA7 | |
| SCHEMBL7914315 | 0.93 | CA12 (0.61) | CA12CA9CA1CA6CA7 | |
| SCHEMBL5831209 | 0.90 | KMT2A (0.59) | CA12CA9CA1CA6CA7 | |
| SCHEMBL7914299 | 0.90 | KMT2A (0.59) | CA12CA9CA1CA6CA7 | |
| SCHEMBL7914273 | 0.88 | KMT2A (0.60) | CA12CA9CA1CA6CA7 | |
| Ether SCHEMBL7917978 | 0.87 | CA9 (0.58) | CA12CA9CA1CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201087-B1 | POLYMERS WHICH CONTAIN COUMARIN OR QUINOLINONE DERIVATIVES AS PHOTOREACTIVE UNITS AS ORIENTING LAYERS FOR LIQUID CRYSTALS; PHOTOCHEMICAL STABILITY AND IMPROVED CONTRAST | ROLIC AG (CH) | 2001-03-13 | — | — | US | disclosed |
| EP-0783537-B1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | ROLIC AG (CH) | 1999-12-01 | — | — | EP | disclosed |