SCHEMBL7918521

SCHEMBL7918521

CSCCC(NC(=O)c1ccc(CN2CCCC2COCc2ccccc2)cc1-c1ccccc1C)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 6/20 0.56
FNTB P49356 6/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7918525 1.00 FNTA (0.56) FNTAFNTB
SCHEMBL7918080 0.91 FNTA (0.59) FNTAFNTB
SCHEMBL7918089 0.91 FNTA (0.59) FNTAFNTB
SCHEMBL7916518 0.91 FNTA (0.59) FNTAFNTB
SCHEMBL7916512 0.91 FNTA (0.59) FNTAFNTB
SCHEMBL7918515 0.89 FNTA (0.56) FNTAFNTB
SCHEMBL7918512 0.89 FNTA (0.56) FNTAFNTB
SCHEMBL7916467 0.88 FNTA (0.60) FNTAFNTB
SCHEMBL7916477 0.88 FNTA (0.60) FNTAFNTB
SCHEMBL7908496 0.87 FNTA (0.54) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6221865-B1 INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. UNIVERSITY OF PITTSBURGH 2001-04-24 US claimed
US-6221865-B1 INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. UNIVERSITY OF PITTSBURGH 2001-04-24 US disclosed