SCHEMBL7918751

SCHEMBL7918751

Clc1ccc2cc3ccc(Cl)c(Cl)c3cc2c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.46
TP53 P04637 3/20 0.41
AHR P35869 5/20 0.38
TSHR P16473 4/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
F11 P03951 1/20 0.33
HTR2B P41595 1/20 0.32
PDE4D Q08499 1/20 0.32
MAOB P27338 1/20 0.32
CMA1 P23946 1/20 0.32
F7 P08709 1/20 0.32
LTA4H P09960 1/20 0.32
F3 P13726 1/20 0.32
NR4A2 P43354 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
TYMS P04818 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5027727 0.85 CYP2A6 (0.61) CYP2A6AHRTSHRALDH1A1CYP3A4
SCHEMBL27740071 0.85 CYP2A6 (0.61) CYP2A6AHRTSHRALDH1A1CYP3A4
SCHEMBL9244984 0.85 CYP2A6 (0.54) CYP2A6TP53AHRTSHRALDH1A1
SCHEMBL5013884 0.85 CYP2A6 (0.48) CYP2A6TP53AHRTSHRALDH1A1
SCHEMBL687156 0.83 CYP2A6 (0.64) CYP2A6AHRTSHRALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL29200220 0.83 CYP2A6 (0.52) CYP2A6TP53AHRTSHRALDH1A1
SCHEMBL4288341 0.79 CYP2A6 (0.68) CYP2A6TP53AHRTSHRALDH1A1
SCHEMBL31665941 0.79 CYP2A6 (0.68) CYP2A6TP53AHRTSHRALDH1A1
SCHEMBL11302716 0.79 CYP2A6 (0.68) CYP2A6TP53AHRTSHRALDH1A1
SCHEMBL11626337 0.79 CYP2A6 (0.68) CYP2A6TP53AHRTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed