SCHEMBL7918802

SCHEMBL7918802

Fc1cccc(-c2ccc(OCI)c3nc(C4CC4)nn23)c1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL510004 0.86 PDE4D (0.74) PDE4D
SCHEMBL509428 0.73 PDE4D (0.65) PDE4D
SCHEMBL508900 0.73 PDE4D (0.76) PDE4D
SCHEMBL510014 0.72 PDE4D (0.70) PDE4D
SCHEMBL508375 0.71 PDE4D (0.77) PDE4D
SCHEMBL509149 0.71 PDE4D (1.00) PDE4D
SCHEMBL509383 0.71 PDE4D (1.00) PDE4D
SCHEMBL509886 0.71 PDE4D (0.76) PDE4D
SCHEMBL508217 0.71 PDE4D (0.67) PDE4D
SCHEMBL7917854 0.70 PDE4D (0.55) PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010069322-A1 TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES LEO PHARMA A/S (DK) 2010-06-24 WO disclosed