Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703929 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2PORCNKMT2AMAPTHSD17B10 | |
| SCHEMBL6173007 | 0.95 | SMN1; SMN2 (0.46) | SMN1; SMN2PORCNKMT2AMAPTHSD17B10 | |
| SCHEMBL630857 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2PORCNKMT2AMAPTHSD17B10 | |
| SCHEMBL432319 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2PORCNKMT2AMAPTHSD17B10 | |
| SCHEMBL15664724 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2PORCNKMT2AMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL28132801 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2PORCNKMT2AMAPTHSD17B10 | |
| SCHEMBL15665079 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2PORCNKMT2AMAPTHSD17B10 | |
| SCHEMBL15665299 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2PORCNKMT2AMAPTHSD17B10 | |
| SCHEMBL29507440 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2PORCNKMT2AMAPTHSD17B10 | |
| SCHEMBL25262222 | 0.81 | TDP1 (0.45) | SMN1; SMN2PORCNKMT2AMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278840-B | Pyrrolo [2,3-B ] pyridine compounds and their use for the treatment of cancer | 癌症研究科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| US-6242262-B1 | MIXING DISCRETE SOLID SUPPORTS, EACH HAVING DIFFERENT ORGANIC COMPOUND, WITH REACTION SOLUTION SO THAT SUPPORTS ARE AT AN INTERFACE IN VESSEL; THEN DETECTING TEMPERATURE CHANGE OF A SOLID SUPPORT AS INDICATION OF AN ACTIVE CATALYST | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2001-06-05 | — | — | US | disclosed |
| WO-1999021957-A9 | METHOD AND APPARATUS FOR SCREENING CATALYST LIBRARIES | UNIV NORTH CAROLINA (US) | 1999-08-12 | — | — | WO | disclosed |
| WO-1999021957-A1 | METHOD AND APPARATUS FOR SCREENING CATALYST LIBRARIES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-05-06 | — | — | WO | disclosed |
| EP-0538931-A2 | Curing catalyst for the reaction between carboxyl functional polymers and epoxy functional compounds for use in the preparation of powder coatings | DSM N.V. (NL) | 1993-04-28 | — | — | EP | disclosed |