Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924645 | 0.88 | POLB (0.40) | POLBLMNACYP1A2ALDH1A1KMT2A | |
| SCHEMBL7927360 | 0.87 | POLB (0.42) | POLBCYP1A2KMT2AMAPTACHE | |
| SCHEMBL7927405 | 0.78 | POLB (0.55) | POLBLMNACYP1A2ALDH1A1KMT2A | |
| SCHEMBL27864062 | 0.76 | POLB (0.47) | POLBLMNACYP1A2ALDH1A1KMT2A | |
| SCHEMBL7928102 | 0.74 | POLB (0.42) | POLBLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL7919158 | 0.74 | POLB (0.42) | POLBCYP1A2KMT2AMAPTACHE | |
| SCHEMBL7927256 | 0.74 | RET (0.36) | POLBLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL30781736 | 0.73 | KMT2A (0.50) | POLBCYP1A2ALDH1A1KMT2A | |
| SCHEMBL29779340 | 0.73 | KMT2A (0.50) | POLBCYP1A2ALDH1A1KMT2A | |
| SCHEMBL47693 | 0.73 | KMT2A (0.50) | POLBCYP1A2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0867454-B1 | POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS | IDEMITSU KOSAN CO (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-6075102-A | Polymerization catalyst and process for producing polymers | IDEMITSU KOSAN CO., LTD. (JP) | 2000-06-13 | — | — | US | disclosed |
| EP-0867454-A1 | POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-09-30 | — | — | EP | disclosed |