Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | FAP | Q12884 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935838 | 0.90 | DPP4 (0.57) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL29361968 | 0.90 | DPP4 (0.72) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL15344691 | 0.90 | DPP4 (0.57) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL30535978 | 0.90 | DPP4 (0.72) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3715380 | 0.90 | DPP4 (0.72) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL1509255 | 0.90 | DPP4 (0.72) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL5266044 | 0.89 | DPP4 (0.70) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL5935836 | 0.88 | DPP4 (0.72) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL5935877 | 0.88 | DPP4 (0.72) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL20008504 | 0.85 | DPP4 (0.59) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010078440-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF N-ACYLATED-4-ARYL BETA-AMINO ACID DERIVATIVES | CHIRAL QUEST, INC. (US) | 2010-07-08 | — | — | WO | disclosed |