⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353253 | 0.74 | — | — | |
| SCHEMBL1817212 | 0.70 | — | — | |
| SCHEMBL790340 | 0.70 | — | — | |
| SCHEMBL352005 | 0.70 | — | — | |
| SCHEMBL790677 | 0.70 | — | — | |
| SCHEMBL1526608 | 0.70 | — | — | |
| SCHEMBL17797275 | 0.67 | — | — | |
| SCHEMBL790947 | 0.67 | — | — | |
| SCHEMBL797400 | 0.67 | — | — | |
| SCHEMBL352434 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191449-A1 | NOVEL COMPOUNDS AS REARRANGED DURING TRANSFECTION (RET) INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2017-07-19 | — | — | EP | disclosed |
| EP-2550264-B1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2016-06-08 | — | — | EP | disclosed |
| WO-2016037578-A1 | NOVEL COMPOUNDS AS REARRANGED DURING TRANSFECTION (RET) INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2016-03-17 | — | — | WO | disclosed |
| US-9040537-B2 | Pyridazine compounds for controlling invertebrate pests | BASF SE (DE) | 2015-05-26 | — | — | US | disclosed |
| EP-2615917-A2 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS III | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| US-20130180014-A1 | Pyridine Compounds for Controlling Invertebrate Pests III | BASF SE (DE) | 2013-07-11 | — | — | US | disclosed |
| EP-2550264-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2013-01-30 | — | — | EP | disclosed |
| US-20130012380-A1 | Pyridazine Compounds For Controlling Invertebrate Pests | BASF SE (DE) | 2013-01-10 | — | — | US | disclosed |
| WO-2012034959-A2 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS III | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011117286-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-09-29 | — | — | WO | disclosed |
| EP-0993452-B1 | ANGIOGENESIS INHIBITING 5-SUBSTITUTED-1,2,4-THIADIAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2007-09-05 | — | — | EP | disclosed |
| US-7208503-B2 | Angiogenesis inhibiting 5-substituted-1,2,4-thiadiazolyl derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-04-24 | — | — | US | disclosed |
| US-6833369-B2 | Treatment of ocular neovascular diseases, neovascular glaucoma, diabetic retinopathy, | JANSSEN PHARMACEUTICA, NV (BE) | 2004-12-21 | — | — | US | disclosed |
| US-20040009987-A9 | ANGIOGENESIS INHIBITING 5-SUBSTITUTED-1,2,4,-THIADIAZOLYL DERIVATIVES | STOKBROEKX RAYMOND ANTOINE (BE) | 2004-01-15 | — | — | US | disclosed |
| US-20030181460-A1 | Angiogenesis inhibiting 5-substituted-1,2,4-thiadiazolyl derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-09-25 | — | — | US | disclosed |
| US-20020061890-A1 | Angiogenesis inhibiting 5-substituted-1,2,4,-thiadiazolyl derivatives | STOKBROEKX RAYMOND ANTOINE (BE) | 2002-05-23 | — | — | US | disclosed |
| EP-0993452-A1 | ANGIOGENESIS INHIBITING 5-SUBSTITUTED-1,2,4-THIADIAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998058919-A1 | ANGIOGENESIS INHIBITING 5-SUBSTITUTED-1,2,4-THIADIAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-12-30 | — | — | WO | disclosed |