Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 19/20 | 1.00 |
| ▸ | CDK2 | P24941 | 19/20 | 1.00 |
| ▸ | CCNA1 | P78396 | 19/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5867707 | 0.90 | CCNA2 (0.82) | CCNA2CDK2CCNA1 | |
| SCHEMBL5867924 | 0.88 | CCNA2 (1.00) | CCNA2CDK2CCNA1 | |
| SCHEMBL5868051 | 0.88 | CCNA2 (0.78) | CCNA2CDK2CCNA1 | |
| SCHEMBL5867578 | 0.88 | CCNA2 (0.78) | CCNA2CDK2CCNA1 | |
| SCHEMBL5867729 | 0.88 | CCNA2 (0.78) | CCNA2CDK2CCNA1 | |
| SCHEMBL4314346 | 0.87 | CCNA2 (1.00) | CCNA2CDK2CCNA1 | |
| SCHEMBL5867521 | 0.87 | CCNA2 (1.00) | CCNA2CDK2CCNA1NPC1RAB9A | |
| SCHEMBL5868066 | 0.85 | CCNA2 (0.78) | CCNA2CDK2CCNA1 | |
| SCHEMBL5867929 | 0.85 | CCNA2 (0.74) | CCNA2CDK2CCNA1 | |
| SCHEMBL5867556 | 0.85 | CDK2 (0.85) | CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218418-B1 | THERAPY OF CELL PROLIFERATIVE DISORDERS ASSOCIATED WITH AN ALTERED CELL DEPENDENT KINASE ACTIVITY BY ADMINISTERING AMINO PYRAZOLE DERIVATIVE TO MAMMAL | PHARMACIA & UPJOHN S.P.A (IT) | 2001-04-17 | — | — | US | disclosed |