Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 8/20 | 0.52 |
| ▸ | NPY1R | P25929 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
| ▸ | MASP2 | O00187 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16181609 | 1.00 | FURIN (0.52) | FURINNPY1RF2MASP2ITGB3 | |
| SCHEMBL16181237 | 1.00 | FURIN (0.52) | FURINNPY1RF2MASP2ITGB3 | |
| SCHEMBL16181249 | 0.96 | FURIN (0.49) | FURINNPY1RF2MASP2ITGB3 | |
| SCHEMBL16181263 | 0.96 | FURIN (0.49) | FURINNPY1RF2MASP2ITGB3 | |
| SCHEMBL16181278 | 0.96 | FURIN (0.54) | FURINNPY1RITGB3ITGA2BNPY2R | |
| SCHEMBL16181274 | 0.94 | NPY1R (0.51) | FURINNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL16181255 | 0.94 | NPY1R (0.51) | FURINNPY1RF2MASP2ITGB3 | |
| SCHEMBL16181267 | 0.93 | FURIN (0.52) | FURINNPY1RITGB3ITGA2BNPY2R | |
| SCHEMBL16181256 | 0.93 | NPY1R (0.58) | FURINNPY1RF2MASP2ITGB3 | |
| SCHEMBL16181266 | 0.93 | NPY1R (0.49) | FURINNPY1RF2MASP2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048941-A2 | N-TERMINALLY MODIFIED TETRAPEPTIDE DERIVATIVES HAVING A C-TERMINAL ARGININE MIMETIC | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2010-05-06 | — | — | WO | disclosed |