Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25811504 | 0.81 | HCRTR1 (0.74) | HCRTR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7920891 | 0.81 | HCRTR1 (0.66) | HCRTR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL30402755 | 0.81 | HCRTR1 (1.00) | HCRTR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL2161594 | 0.81 | HCRTR1 (1.00) | HCRTR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL68639 | 0.80 | KDM4E (0.85) | HCRTR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL9907547 | 0.77 | HCRTR1 (0.82) | HCRTR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11615811 | 0.76 | HCRTR1 (0.71) | HCRTR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL2161298 | 0.76 | HCRTR1 (0.74) | HCRTR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL3199051 | 0.75 | KDM4E (0.64) | HCRTR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL9907621 | 0.75 | HCRTR1 (0.69) | HCRTR1KDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228868-B1 | ANTICARCINOGENIC AND ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-08 | — | — | US | disclosed |
| WO-2000006556-A1 | SUBSTITUTED OXAZOLINES AS ANTIPROLIFERATIVE AGENTS | ABBOTT LABORATORIES (US) | 2000-02-10 | — | — | WO | disclosed |