Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 18/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.56 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.56 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.56 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.56 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.56 |
| ▸ | ATR | Q13535 | 5/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15393723 | 1.00 | MTOR (0.59) | MTORPIK3CAPIK3CGRICTORRPTOR | |
| SCHEMBL14790912 | 0.93 | MTOR (0.71) | MTORPIK3CAPIK3CGRICTORRPTOR | |
| SCHEMBL3145907 | 0.88 | MTOR (0.64) | MTORPIK3CAPIK3CGRICTORRPTOR | |
| SCHEMBL7920905 | 0.88 | MTOR (0.64) | MTORPIK3CAPIK3CGRICTORRPTOR | |
| Hydrochloric Acid SCHEMBL1359560 | 0.88 | MTOR (0.64) | MTORPIK3CAPIK3CGRICTORRPTOR | |
| SCHEMBL7917870 | 0.87 | PIK3CA (0.51) | MTORPIK3CAPIK3CGATRAURKB | |
| SCHEMBL1359067 | 0.85 | MTOR (0.80) | MTORPIK3CAPIK3CGRICTORRPTOR | |
| SCHEMBL7917261 | 0.83 | MTOR (0.70) | MTORPIK3CAPIK3CGRICTORRPTOR | |
| SCHEMBL16684433 | 0.83 | MTOR (0.65) | MTORPIK3CAPIK3CGRICTORRPTOR | |
| SCHEMBL14794908 | 0.82 | MTOR (0.78) | MTORPIK3CAPIK3CGATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056320-A2 | PI3K/MTOR KINASE INHIBITORS | TYROGENEX, INC. (US) | 2010-05-20 | — | — | WO | disclosed |