Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 17/20 | 0.67 |
| ▸ | HTR2C | P28335 | 17/20 | 0.67 |
| ▸ | HTR2B | P41595 | 17/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917201 | 0.91 | HTR2A (0.65) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL2339512 | 0.89 | HTR2A (0.84) | HTR2AHTR2CHTR2B | |
| SCHEMBL2339264 | 0.88 | HTR2A (0.67) | HTR2AHTR2CHTR2B | |
| SCHEMBL2342239 | 0.88 | HTR2A (0.67) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL2339143 | 0.88 | HTR2A (0.82) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL2342793 | 0.86 | HTR2A (0.65) | HTR2AHTR2CHTR2B | |
| SCHEMBL2341907 | 0.86 | HTR2C (0.65) | HTR2AHTR2CHTR2B | |
| SCHEMBL2346213 | 0.85 | HTR2C (0.64) | HTR2AHTR2CHTR2BHRH2HRH3 | |
| SCHEMBL2342956 | 0.85 | HTR2C (0.64) | HTR2AHTR2CHTR2BHRH3 | |
| Hydrochloric Acid SCHEMBL2340227 | 0.85 | HTR2C (0.63) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053825-A1 | 2-AMINOPYRIMIDINE COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-14 | — | — | WO | disclosed |