Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924103 | 0.90 | PDE4D (0.52) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7926839 | 0.89 | PDE4D (0.57) | PDE4APDE4D | |
| SCHEMBL509391 | 0.88 | PDE4D (0.60) | PDE4APDE4D | |
| SCHEMBL509944 | 0.83 | PDE4D (0.75) | PDE4APDE4D | |
| SCHEMBL7919041 | 0.82 | PDE4D (0.62) | PDE4D | |
| SCHEMBL510003 | 0.78 | PDE4D (0.61) | PDE4D | |
| SCHEMBL7927497 | 0.76 | PDE4D (0.62) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7931731 | 0.75 | PDE4D (0.61) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL509307 | 0.75 | PDE4D (0.58) | PDE4D | |
| SCHEMBL508880 | 0.74 | PDE4D (0.79) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069322-A1 | TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES | LEO PHARMA A/S (DK) | 2010-06-24 | — | — | WO | disclosed |