⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516824 | 0.79 | — | — | |
| SCHEMBL12879663 | 0.71 | — | — | |
| SCHEMBL516547 | 0.69 | — | — | |
| SCHEMBL9063900 | 0.69 | — | — | |
| SCHEMBL25451635 | 0.67 | — | — | |
| SCHEMBL26318846 | 0.65 | — | — | |
| SCHEMBL26867582 | 0.63 | — | — | |
| SCHEMBL24300304 | 0.62 | — | — | |
| SCHEMBL18454857 | 0.62 | — | — | |
| SCHEMBL1704859 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232338-B1 | 4-Mercaptopyrrolidine derivatives as farnesyl transferase inhibitors | ZENECA LIMITED (GB) | 2001-05-15 | — | — | US | disclosed |