Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913506 | 0.91 | ADORA2A (0.31) | ADORA2AADORA1P2RX3 | |
| SCHEMBL6193114 | 0.67 | CACNA1D (0.35) | — | |
| SCHEMBL7922195 | 0.62 | ADORA2A (0.37) | ADORA2AADORA1 | |
| SCHEMBL3780105 | 0.60 | MAPT (0.33) | — | |
| SCHEMBL7115170 | 0.58 | — | — | |
| SCHEMBL1281643 | 0.57 | NPC1 (0.64) | — | |
| SCHEMBL6677390 | 0.56 | MEN1 (0.31) | — | |
| SCHEMBL6071954 | 0.55 | CACNA1D (0.30) | — | |
| SCHEMBL14752348 | 0.55 | KDM5C (0.54) | — | |
| SCHEMBL6679649 | 0.55 | CACNA1D (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001766-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2001-04-04 | — | — | EP | disclosed |
| EP-1001766-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999001127-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-14 | — | — | WO | disclosed |