Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790304 | 0.81 | — | — | |
| SCHEMBL791224 | 0.78 | — | — | |
| SCHEMBL2068464 | 0.73 | MEN1 (0.33) | MEN1CYP1A2KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL791961 | 0.73 | MEN1 (0.33) | MEN1CYP1A2KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL790796 | 0.72 | POLB (0.38) | MEN1CYP1A2KMT2A | |
| SCHEMBL791089 | 0.72 | MEN1 (0.32) | MEN1CYP1A2KMT2A | |
| SCHEMBL791156 | 0.72 | MEN1 (0.32) | MEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL790404 | 0.71 | KDM4E (0.31) | MEN1CYP1A2KMT2A | |
| SCHEMBL797687 | 0.71 | HTR2A (0.31) | — | |
| SCHEMBL790070 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550264-B1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2016-06-08 | — | — | EP | disclosed |
| US-9040537-B2 | Pyridazine compounds for controlling invertebrate pests | BASF SE (DE) | 2015-05-26 | — | — | US | disclosed |
| EP-2615917-A2 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS III | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| US-20130180014-A1 | Pyridine Compounds for Controlling Invertebrate Pests III | BASF SE (DE) | 2013-07-11 | — | — | US | disclosed |
| EP-2550264-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2013-01-30 | — | — | EP | disclosed |
| US-20130012380-A1 | Pyridazine Compounds For Controlling Invertebrate Pests | BASF SE (DE) | 2013-01-10 | — | — | US | disclosed |
| WO-2012034959-A2 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS III | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011117286-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012380-A1 | Pyridazine Compounds For Controlling Invertebrate Pests | GRIN2C, GRIN2A, NR2C2 | MEN1 4195/4885CYP1A2 98/4885KMT2A 524/4885 |
| US-20130180014-A1 | Pyridine Compounds for Controlling Invertebrate Pests III | CHRM1, CHRM2, GRIN2C | MEN1 4198/4885CYP1A2 127/4885KMT2A 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.