Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 12/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16156074 | 0.83 | TSHR (0.40) | ALDH1A1TDP1 | |
| SCHEMBL7753385 | 0.80 | FFAR1 (0.48) | CETPFFAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL20357212 | 0.75 | SLC1A3 (0.36) | ALDH1A1 | |
| SCHEMBL9848766 | 0.72 | FFAR1 (0.47) | CETPFFAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL10799979 | 0.72 | FFAR1 (0.53) | CETPFFAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL2093737 | 0.72 | KDM4E (0.55) | CETPFFAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL27417613 | 0.72 | PPARG (0.52) | CETPFFAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL5407250 | 0.71 | KDM4E (0.58) | CETPKDM4EALDH1A1TDP1PTGES | |
| SCHEMBL2354114 | 0.71 | TSHR (0.56) | CETPFFAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL9339511 | 0.71 | FFAR1 (0.46) | CETPFFAR1KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |