Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | DAGLB | Q8NCG7 | 2/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2538398 | 0.89 | PDE8B (0.42) | KDM4EHPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL2513353 | 0.79 | HCRTR1 (0.45) | TSHRKMT2A | |
| SCHEMBL8160273 | 0.79 | KDM4E (0.51) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL7923409 | 0.79 | KDM4E (0.39) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL2509592 | 0.79 | HCRTR2 (0.42) | KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL2489210 | 0.79 | HCRTR2 (0.42) | TSHRKMT2A | |
| SCHEMBL2489214 | 0.79 | HCRTR2 (0.42) | TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL2533566 | 0.79 | HCRTR1 (0.44) | TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL2536527 | 0.78 | HCRTR2 (0.42) | KDM4EHPGDHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2490041 | 0.78 | HCRTR2 (0.41) | TSHRKMT2AJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072722-A1 | PIPERIDINE DERIVATIVES USEFUL AS OREXIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2010-07-01 | — | — | WO | disclosed |