Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinic Acid SCHEMBL12026338 | 1.00 | HSD17B10 (0.39) | HSD17B10AKR1B1KDM4EPTPN1ALDH1A1 | |
| Quinic Acid SCHEMBL10125264 | 1.00 | HSD17B10 (0.39) | HSD17B10AKR1B1KDM4EPTPN1ALDH1A1 | |
| Quinic Acid SCHEMBL6656460 | 1.00 | HSD17B10 (0.39) | HSD17B10AKR1B1KDM4EPTPN1ALDH1A1 | |
| Quinic Acid SCHEMBL39556 | 1.00 | HSD17B10 (0.39) | HSD17B10AKR1B1KDM4EPTPN1ALDH1A1 | |
| Quinic Acid SCHEMBL614369 | 1.00 | HSD17B10 (0.39) | HSD17B10AKR1B1KDM4EPTPN1ALDH1A1 | |
| Quinic Acid SCHEMBL19490687 | 1.00 | HSD17B10 (0.39) | HSD17B10AKR1B1KDM4EPTPN1ALDH1A1 | |
| Quinic Acid SCHEMBL14960616 | 1.00 | HSD17B10 (0.39) | HSD17B10AKR1B1KDM4EPTPN1ALDH1A1 | |
| Quinic Acid SCHEMBL1286207 | 1.00 | HSD17B10 (0.39) | HSD17B10AKR1B1KDM4EPTPN1ALDH1A1 | |
| Quinic Acid SCHEMBL39555 | 1.00 | HSD17B10 (0.39) | HSD17B10AKR1B1KDM4EPTPN1ALDH1A1 | |
| Quinic Acid SCHEMBL12045452 | 1.00 | HSD17B10 (0.39) | HSD17B10AKR1B1KDM4EPTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957078-B1 | Process for the preparation of shikimic acid and its derivatives | HOFFMANN LA ROCHE (CH) | 2001-11-28 | — | — | EP | disclosed |
| EP-0957078-A1 | Process for the preparation of shikimic acid and its derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-17 | — | — | EP | disclosed |